UM6P School of Applied and Engineering Physics Researchers Propose a Novel Enhanced-Raman Spectroscopy based on Black phosphorene (BPERS) for the Sensitive Detection of DNA Nucleotides.

March 25, 2025

The UM6P School of Applied and Engineering Physics, in collaboration with the UM6P_SHCC – Faculty of Medical Sciences & UM6P Hospitals, has proposed a novel Enhanced Raman Spectroscopy (BPERS) for the sensitive detection of DNA nucleotides based on Black Phosphorene 2D Materials.

This study demonstrates that BPERS, based on black phosphorene (BP), offers superior enhancement for biomolecular detection compared to other 2D materials, such as graphene and molybdenum disulfide.

The researchers showed that black phosphorene significantly amplifies the Raman signals of DNA nucleotides, enabling more sensitive and accurate detection of individual nucleotides.

This research highlights black phosphorene as a promising platform for biosensor applications and advanced diagnostics.

The complete study is available in Applied Physics Letters (APL): DOI: 10.1063/5.0264525